{"id":4820,"date":"2026-05-01T21:51:31","date_gmt":"2026-05-01T21:51:31","guid":{"rendered":"https:\/\/fehv.org\/?p=4820"},"modified":"2026-05-01T21:51:33","modified_gmt":"2026-05-01T21:51:33","slug":"metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer","status":"publish","type":"post","link":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/","title":{"rendered":"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer"},"content":{"rendered":"\n

Metabolic syndrome is characterized by an increase in abdominal diameter, as well as increased blood pressure, triglycerides, glucose, and a decrease good colesterol (HDL). Approximately 70 percent of patients with fatty liver have metabolic syndrome.<\/p>\n\n\n\n

The risk of developing fatty liver<\/a><\/strong> disease is between 4 and 11 times higher in patients with metabolic syndrome. In addition, liver disease is more aggressive in patients with metabolic syndrome and fatty liver disease.<\/p>\n\n\n\n

Patients with metabolic syndrome have a higher risk of developing cancers of the gastrointestinal tract, as has been demonstrated in several studies.<\/p>\n\n\n\n

A study published in the journal Hepatology<\/a><\/strong> investigated the posible relationship between metabolic syndrome and bile duct c\u00e1ncer (cholangiocarcinoma). The study included 4,932,211 individuals recruited through routine checkups, of whom 2,029,759 had metabolic syndrome. Patients with metabolic syndrome showed a significantly higher incidence of cholangiocarcinoma<\/strong>. This association was most significant among individuals aged 50 to 59 years.<\/p>\n\n\n\n

In summary, metabolic syndrome is associated with a higher probability of\u00a0 developing bile duct cancer. Given the high frequency with which metabolic syndrome is associated with fatty liver<\/strong>, between 40% and 70% of patients with metabolic syndrome have fatty liver, and this relationship must be extended to cholangiocarcinoma (in fact, other studies have demonstrated an association between fatty liver and cholangiocarcinoma). Both Dr. Carre\u00f1o and the foundation’s doctors agree with these results. In this regard, it is important to treat the various parameters that make up metabolic syndrome (blood pressure, waist circumference, triglyceride levels, glucose, and HDL cholesterol) to reduce the probability of developing bile duct cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"Metabolic syndrome increases the risk of bile duct cancer, especially in patients with fatty liver, where liver disease tends to be more aggressive.","protected":false},"author":1,"featured_media":4818,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1127,623],"tags":[],"class_list":["post-4820","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diagnosis","category-fatty-liver"],"acf":[],"yoast_head":"\nMetabolic syndrome, fatty liver, and their relationship to bile duct cancer - Cl\u00ednica FEHV<\/title>\n<meta name=\"description\" content=\"Metabolic syndrome and bile duct cancer are linked; learn how risk increases in patients with fatty liver disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer\" \/>\n<meta property=\"og:description\" content=\"Metabolic syndrome and bile duct cancer are linked; learn how risk increases in patients with fatty liver disease.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"Cl\u00ednica FEHV\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/pages\/Fundacion%20Para%20el%20Estudio%20de%20las%20Hepatitis%20Virales\/228605694153917\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-01T21:51:31+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-01T21:51:33+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1280\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ifranco\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ifranco\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/\"},\"author\":{\"name\":\"ifranco\",\"@id\":\"https:\/\/fehv.org\/#\/schema\/person\/5e92ddd4a04516dab21fb5b6fa90b777\"},\"headline\":\"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer\",\"datePublished\":\"2026-05-01T21:51:31+00:00\",\"dateModified\":\"2026-05-01T21:51:33+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/\"},\"wordCount\":260,\"publisher\":{\"@id\":\"https:\/\/fehv.org\/#organization\"},\"image\":{\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg\",\"articleSection\":[\"Diagnosis\",\"Fatty liver\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/\",\"url\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/\",\"name\":\"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer - Cl\u00ednica FEHV\",\"isPartOf\":{\"@id\":\"https:\/\/fehv.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg\",\"datePublished\":\"2026-05-01T21:51:31+00:00\",\"dateModified\":\"2026-05-01T21:51:33+00:00\",\"description\":\"Metabolic syndrome and bile duct cancer are linked; learn how risk increases in patients with fatty liver disease.\",\"breadcrumb\":{\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#primaryimage\",\"url\":\"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg\",\"contentUrl\":\"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg\",\"width\":1920,\"height\":1280,\"caption\":\"Imagen de un laboratorio y ensayo cl\u00ednico\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\/\/fehv.org\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/fehv.org\/#website\",\"url\":\"https:\/\/fehv.org\/\",\"name\":\"Cl\u00ednica FEHV\",\"description\":\"Web de la Cl\u00ednica de la Fundaci\u00f3n para el Estudio de las Hepatitis Virales\",\"publisher\":{\"@id\":\"https:\/\/fehv.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/fehv.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/fehv.org\/#organization\",\"name\":\"Fundaci\u00f3n para el Estudio de las Hepatitis Virales - FEHV\",\"url\":\"https:\/\/fehv.org\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/fehv.org\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/fehv.org\/wp-content\/uploads\/2021\/03\/logo_fib-4.png\",\"contentUrl\":\"https:\/\/fehv.org\/wp-content\/uploads\/2021\/03\/logo_fib-4.png\",\"width\":47,\"height\":73,\"caption\":\"Fundaci\u00f3n para el Estudio de las Hepatitis Virales - FEHV\"},\"image\":{\"@id\":\"https:\/\/fehv.org\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/pages\/Fundacion Para el Estudio de las Hepatitis Virales\/228605694153917\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/fehv.org\/#\/schema\/person\/5e92ddd4a04516dab21fb5b6fa90b777\",\"name\":\"ifranco\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/fehv.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/aa877054d0216c55e7104c50647e81a8?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/aa877054d0216c55e7104c50647e81a8?s=96&d=mm&r=g\",\"caption\":\"ifranco\"}}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer - Cl\u00ednica FEHV","description":"Metabolic syndrome and bile duct cancer are linked; learn how risk increases in patients with fatty liver disease.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/","og_locale":"en_US","og_type":"article","og_title":"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer","og_description":"Metabolic syndrome and bile duct cancer are linked; learn how risk increases in patients with fatty liver disease.","og_url":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/","og_site_name":"Cl\u00ednica FEHV","article_publisher":"https:\/\/www.facebook.com\/pages\/Fundacion%20Para%20el%20Estudio%20de%20las%20Hepatitis%20Virales\/228605694153917\/","article_published_time":"2026-05-01T21:51:31+00:00","article_modified_time":"2026-05-01T21:51:33+00:00","og_image":[{"width":1920,"height":1280,"url":"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg","type":"image\/jpeg"}],"author":"ifranco","twitter_card":"summary_large_image","twitter_misc":{"Written by":"ifranco","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#article","isPartOf":{"@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/"},"author":{"name":"ifranco","@id":"https:\/\/fehv.org\/#\/schema\/person\/5e92ddd4a04516dab21fb5b6fa90b777"},"headline":"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer","datePublished":"2026-05-01T21:51:31+00:00","dateModified":"2026-05-01T21:51:33+00:00","mainEntityOfPage":{"@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/"},"wordCount":260,"publisher":{"@id":"https:\/\/fehv.org\/#organization"},"image":{"@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg","articleSection":["Diagnosis","Fatty liver"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/","url":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/","name":"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer - Cl\u00ednica FEHV","isPartOf":{"@id":"https:\/\/fehv.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#primaryimage"},"image":{"@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg","datePublished":"2026-05-01T21:51:31+00:00","dateModified":"2026-05-01T21:51:33+00:00","description":"Metabolic syndrome and bile duct cancer are linked; learn how risk increases in patients with fatty liver disease.","breadcrumb":{"@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#primaryimage","url":"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg","contentUrl":"https:\/\/fehv.org\/wp-content\/uploads\/2026\/05\/relacion-higado-graso-cancer-biliar.jpg","width":1920,"height":1280,"caption":"Imagen de un laboratorio y ensayo cl\u00ednico"},{"@type":"BreadcrumbList","@id":"https:\/\/fehv.org\/en\/metabolic-syndrome-fatty-liver-relationship-bile-duct-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/fehv.org\/en\/"},{"@type":"ListItem","position":2,"name":"Metabolic syndrome, fatty liver, and their relationship to bile duct cancer"}]},{"@type":"WebSite","@id":"https:\/\/fehv.org\/#website","url":"https:\/\/fehv.org\/","name":"Cl\u00ednica FEHV","description":"Web de la Cl\u00ednica de la Fundaci\u00f3n para el Estudio de las Hepatitis Virales","publisher":{"@id":"https:\/\/fehv.org\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/fehv.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/fehv.org\/#organization","name":"Fundaci\u00f3n para el Estudio de las Hepatitis Virales - FEHV","url":"https:\/\/fehv.org\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/fehv.org\/#\/schema\/logo\/image\/","url":"https:\/\/fehv.org\/wp-content\/uploads\/2021\/03\/logo_fib-4.png","contentUrl":"https:\/\/fehv.org\/wp-content\/uploads\/2021\/03\/logo_fib-4.png","width":47,"height":73,"caption":"Fundaci\u00f3n para el Estudio de las Hepatitis Virales - FEHV"},"image":{"@id":"https:\/\/fehv.org\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/pages\/Fundacion Para el Estudio de las Hepatitis Virales\/228605694153917\/"]},{"@type":"Person","@id":"https:\/\/fehv.org\/#\/schema\/person\/5e92ddd4a04516dab21fb5b6fa90b777","name":"ifranco","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/fehv.org\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/aa877054d0216c55e7104c50647e81a8?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/aa877054d0216c55e7104c50647e81a8?s=96&d=mm&r=g","caption":"ifranco"}}]}},"_links":{"self":[{"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/posts\/4820"}],"collection":[{"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/comments?post=4820"}],"version-history":[{"count":1,"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/posts\/4820\/revisions"}],"predecessor-version":[{"id":4821,"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/posts\/4820\/revisions\/4821"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/media\/4818"}],"wp:attachment":[{"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/media?parent=4820"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/categories?post=4820"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fehv.org\/en\/wp-json\/wp\/v2\/tags?post=4820"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}