{"id":4048,"date":"2023-04-14T08:37:13","date_gmt":"2023-04-14T08:37:13","guid":{"rendered":"https:\/\/fehv.org\/?p=4048"},"modified":"2023-04-14T08:37:15","modified_gmt":"2023-04-14T08:37:15","slug":"new-drug-treatment-fatty-liver","status":"publish","type":"post","link":"https:\/\/fehv.org\/en\/new-drug-treatment-fatty-liver\/","title":{"rendered":"New drug for the treatment of fatty liver"},"content":{"rendered":"\n

Fatty liver, in its form of steatohepatitis (fat + inflammation + liver necrosis) can be a very aggressive disease and progress to liver cirrhosis and liver cancer. The prevalence of fatty liver has been increasing in recent years and affects 20-30% of the general population. Fatty liver<\/a><\/strong> is also associated with high blood pressure, cardiovascular diseases and a greater possibility of colon cancer and chronic kidney disease. For these reasons it is necessary to have effective drugs for the treatment of the disease.<\/p>\n\n\n\n

A study on the use of vonafexor for the treatment of the fatty liver disease has been published in the Journal of Hepatology<\/a><\/strong>. One hundred and twenty three patients with steatohepatitis were included into various groups and received vonafexor<\/strong> at doses of 100mg, 200mg, 400mg or placebo for 12 weeks.<\/p>\n\n\n\n

How this new drug for the treatment of fatty liver works<\/strong><\/h2>\n\n\n\n

The authors found that vonafexor significantly decreased liver fat content<\/strong> compared to the placebo group. The drug also significantly decreased the levels of inflammatory markers. In addition, at 12 weeks of treatment, the patients who received vonafexor presented a significant reduction in weight and abdominal circumference in relation to the placebo group. The most frequent side effect suffered by patients treated with vonafexor was pruritus (61% of cases), compared with 6% of those who received placebo.<\/p>\n\n\n\n

The data indicate that vonafexor is a promising drug<\/strong> for the treatment of steatohepatitis, although further studies need to be carried out with more patients and perhaps it has to be administered for a longer period of time.<\/p>\n","protected":false},"excerpt":{"rendered":"We analyze the effects of new drug for the treatment of fatty liver, vonarefox.","protected":false},"author":1,"featured_media":2755,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[623,621,624],"tags":[],"class_list":["post-4048","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fatty-liver","category-news","category-treatments"],"acf":[],"yoast_head":"\nNew drug for the treatment of fatty liver - Cl\u00ednica FEHV<\/title>\n<meta name=\"description\" content=\"Vonarefox is the new treatment for fatty liver, which considerably decreases the fat content and has a promising future.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fehv.org\/en\/new-drug-treatment-fatty-liver\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New drug for the treatment of fatty liver\" \/>\n<meta property=\"og:description\" content=\"Vonarefox is the new treatment for fatty liver, which considerably decreases the fat content and has a promising future.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fehv.org\/en\/new-drug-treatment-fatty-liver\/\" \/>\n<meta property=\"og:site_name\" content=\"Cl\u00ednica FEHV\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/clinicaFEHV\/\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-14T08:37:13+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-04-14T08:37:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/fehv.org\/wp-content\/uploads\/2021\/03\/medicina_higado_graso.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"640\" \/>\n\t<meta property=\"og:image:height\" content=\"480\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ifranco\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ifranco\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/fehv.org\\\/en\\\/new-drug-treatment-fatty-liver\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/fehv.org\\\/en\\\/new-drug-treatment-fatty-liver\\\/\"},\"author\":{\"name\":\"ifranco\",\"@id\":\"https:\\\/\\\/fehv.org\\\/#\\\/schema\\\/person\\\/5e92ddd4a04516dab21fb5b6fa90b777\"},\"headline\":\"New drug for the treatment of fatty liver\",\"datePublished\":\"2023-04-14T08:37:13+00:00\",\"dateModified\":\"2023-04-14T08:37:15+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/fehv.org\\\/en\\\/new-drug-treatment-fatty-liver\\\/\"},\"wordCount\":260,\"publisher\":{\"@id\":\"https:\\\/\\\/fehv.org\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/fehv.org\\\/en\\\/new-drug-treatment-fatty-liver\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/fehv.org\\\/wp-content\\\/uploads\\\/2021\\\/03\\\/medicina_higado_graso.jpg\",\"articleSection\":[\"Fatty liver\",\"News\",\"Treatments\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/fehv.org\\\/en\\\/new-drug-treatment-fatty-liver\\\/\",\"url\":\"https:\\\/\\\/fehv.org\\\/en\\\/new-drug-treatment-fatty-liver\\\/\",\"name\":\"New drug for the treatment of fatty liver - 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